Indolizine Derivatives. VI. Indolizines from the Acylative Cyclization of 3-(2-Pyridyl)-2-propen-1-ones and Related Compounds.
نویسندگان
چکیده
منابع مشابه
Silver-catalyzed cyclization of 2-pyridyl alkynyl carbinols with isocyanides: divergent synthesis of indolizines and pyrroles.
Divergent syntheses of indolizines and 2,4-disubstituted pyrroles by the silver-catalyzed cyclization of 2-pyridyl alkynyl carbinols with isocyanides are reported. These methods provide an effective route to highly functionalized indolizines and 2,4-disubstituted pyrroles in good to excellent yields. The 2,4-disubstituted pyrroles are synthesized by an unprecedented regioselective [3+2] cycload...
متن کامل(E)-3-(4-Fluorophenyl)-1-phenyl-2-propen-1-one
In the title compound, C(15)H(11)FO, the configuration of the keto group with respect to the olefinic double bond is s-cis. The dihedral angle between the planes of the two benzene rings is 10.61 (10)°. The crystal packing is stabilized by C-H⋯π inter-actions involving both benzene rings.
متن کاملStructure based Antibacterial Activity Of 1,3-Diaryl-2-Propen-1-Ones And Their Recent Pharmacological Interests
Chemically chalcones are 1,3–diphenyl-2-propene-1-one, containing dual aromatic rings which are linked to each other via carbon bridge system enveloping keto-ethylenic core structure. Owing to the presence of conjugated double bond and electron dense aromatic ring system, the molecule possesses less redox potential; thus greater probability for characteristic electron transfer reactions. Natura...
متن کاملCarcinostatic action of polycarbonyl compounds and their derivatives. I. 3-Ethoxy-2-ketobutyraldehyde and related compounds.
Underwood and co-workers (27) recently re ported that a number of a-ketoaldehydes and closely related compounds were active against Newcastle disease virus (NJKD strain) and in fluenza virus (PR-8 strain) in embryonated eggs. These substances also had potent virus-inactivat ing effects in vitro. Underwood and Weed (28) found that glyoxal and methylglyoxal were active virucides in blood. Consequ...
متن کامل3-(5-Methyl-2-furyl)-1-(p-tolyl)-2-propen-1-one
The title compound, C(15)H(14)O(2), was prepared from 4-methyl-hypnone and 5-methyl-furfural by Clasion-Schmidt condensation. All of the bond lengths and bond angles are in normal ranges. The dihedral angle formed by the benzene ring and furan ring is 5.31 (2).
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Acta Chemica Scandinavica
سال: 1976
ISSN: 0904-213X
DOI: 10.3891/acta.chem.scand.30b-0512